Program Publications
Leta S. Steffen, Jeffery W. Bacher, Yuanlin Peng, Phuong N. Le, Liang-Hao Ding, Paula C. Genik, F. Andrew Ray, Joel S. Bedford, Christina M. Fallgren, Susan M. Bailey, Robert L. Ullrich, Michael M. Weil, Michael D. Story ( 2013) Molecular characterisation of murine acute myeloid leukaemia induced by 56Fe ion and137Cs gamma ray irradiation . Mutagenesis 28(1): 71-79
Neumaier T, Swenson J, Pham C, Polyzos A, Lo AT, Yang P, Dyball J, Asaithamby A, Chen DJ, Bissell MJ, Thalhammer S, Costes SV ( 2012) Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells. PNAS 109(2): 443-8
Yong-Won Kwon, Il-Jin Kim, Di Wu, Jing Lu, William A. Stock Jr, Yueyong Liu, Yurong Huang, Hio Chung Kang, Reyno DelRosario, Kuang-Yu Jen, Jesus Perez-Losada, Guangwei Wei, Allan Balmain, and Jian-Hua Mao ( 2012) Pten Regulates Aurora-A and Cooperates with Fbxw7 in Modulating Radiation-Induced Tumor Development. Molecular Cancer Research 10: 834-844
Feng Yang, Katrina M. Waters, Bobbie-Jo Webb-Robertson, Marianne B. Sowa, Claere von Neubeck, Josh T. Aldrich, Lye Meng Markillie, Rachel M. Wirgau, Marina A. Gritsenko, Rui Zhao, David G. Camp II, Richard D. Smith, David L. Stenoien ( 2012) Quantitative phosphoproteomics identifies filaggrin and other targets of ionizing radiation in a human skin model. Experimental Dermatology 21(5): 352–357
Scott, BR ( 2011) A Guide to Radiation Hazard Evaluation Applied to Fukushima Recovery Workers. Journal of American Physicians and Surgeons 16(3): 71-76
De Lisio, M., Kaczor, J. J., Phan, N., Tarnopolsky, M. A., Boreham, D. R. and Parise, G. ( 2011) Exercise Training Enhances the Skeletal Muscle Response to Radiation-Induced Oxidative Stress. Muscle & Nerve 43: 58-64
Li W, Li F, Huang Q, Shen J, Wolf F, He Y, Liu X, Hu A, Bedford J, Li C-Y ( 2011) Quantitative, Noninvasive Imaging of Radiation-Induced DNA Double-Strand Breaks In Vivo. Cancer Research 71(12): 4130-4137
Nguyen DH, HA Oketch-Rabah, I Illa-Bochaca, FC Geyer, JS Reis-Filho, J-H Mao, SA Ravani, J Zavadil, AD Borowsky, DJ Jerry, KA Dunphy, JH Seo, S Haslam, D Medina, and MH Barcellos-Hoff ( 2011) Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Cancer Latency and Affect Tumor Type. Cancer Cell 19(5): 640-651
Wyrobek AJ, Manohar CF, Krishnan VV, Nelson DO, Furtado MR, Bhattacharya MS, Marchetti F, Coleman M ( 2011) Radiation response networks and pathways in human lymphoblastoid cells exposed from 1 to 10 cGy of acute gamma radiation. Mutation Research 722(2): 119-130
Sonia M. de Toledo, Manuela Buonanno, Min Li, Nesrin Asaad, Yong Qin,Geraldine Gonon, Grace Shim, Mariann Galdass, Yaa Boateng, Jie Zhang,and Edouard I. Azzam ( 2011) The Impact of Adaptive and Non-Targeted Effects in the Biological Responses to Low Dose/Low Fluence Ionizing Radiation: The Modulating Effect of Linear Energy Transfer. Health Physics 100(3): 290-292
Chappell, L. J., Whalen, M.K., Gurai, S., Ponomarev, A., Cucinotta, F.A., and Pluth, J.M. ( 2010) Analysis of Flow Cytometry DNA Damage Response Protein Activation Kinetics after Exposure to X Rays and High-Energy Iron Nuclei.. Radiation Research 174(6): 691-702
Martínez, A., Blanco, B., Carnevale, A., Mora, M.A., Coleman, M.A. Romero-Talamás, C.A. and Frías, S. ( 2010) Assessment of immediate DNA damage to workers occupationally exposed to low dose of ionizing radiation using the Comet Assay. Revista de investigacion clinica 62(1): 23-30
Gridley, D.S., Luo-Owen, X., Rizvi, A., Makinde, A.Y., Pecaut, M.J., Mao, X.W., and Slater, J.M. ( 2010) Low-dose Photon and Simulated Solar Particle Event Proton Effects on Foxp3+ T Regulatory Cells and Other Leukocytes. Technology in Cancer Research and Treatment 9(6): 637-649
Yang F, Waters KM, Miller JH, Gritsenko MA, Zhao R, Du X, Purvine SO, Monroe ME, Wang Y, Camp II DG, Smith RD, Stenoien DL ( 2010) Phosphoproteomics Profiling of Human Skin Fibroblast Cells Reveals Pathways and Proteins Affected by Low Doses of Ionizing Radiation. PLoS One 5(11): e14152
Bai L, Xu S, Chen W, Li Z, Wang X, Tang H, Lin Y ( 2010) Synergistic Cancer Cell Death by Concurrent Hsp90 and c-IAP1 Suppression that Blocks NF-KB and Akt and Activates Apoptosis Pathway. Apoptosis :
Schwartz, JL, Plotnik, D, Slovic, J, Li, T, Racelis, M, Deeg, HJ, Friedman, DL ( 2010) TP53 Codon-72 Polymorphisms Identify Different Radiation Sensitivities to G2-Chromosome Breakage in Human Lymphoblast Cells. Environmental and Molecular Mutagenesis 52(1): 77-80
Thompson, D., Pearson, F., Rao, R., Matthews, D. Albala, A., Wachsmann-Hogiu, S., and Coleman, M.A. ( 2009) A portable hand-held microarray reader for biodetection. Sensors 9: 2524-2537
Kuo W-L, D Das, S Ziyad, S Bhattaharya, WJ Gibb, LM Heiser, A Sadanandam, GV Fontenay, Z Hu, NJ Wang, N Bayani, HS Feiler, H.S., Neve, AJ Wyrobek, PT Spellman, LJ Marton, and JW Gray ( 2009) A Systems Analysis of the Chemosensitivity of Breast Cancer Cells to the Polyamine Analogue PG-11047. BMC Medicine 7: 77
Olga K. Mirzoeva, Debopriya Das, Laura M. Heiser, Sanchita Bhattacharya, Doris Siwak, Rina Gendelman, Nora Bayani, Nicholas J. Wang, Richard M. Neve, Yinghui Guan, Zhi Hu, Zachary Knight, Heidi S. Feiler, Philippe Gascard, Bahram Parvin, Paul T. Spellman, Kevan M. Shokat, Andrew J. Wyrobek, Mina J. Bissell, Frank McCormick, Wen-Lin Kuo, Gordon B. Mills, Joe W. Gray, and W. Michael Korn ( 2009) Basal Subtype and MAPK/ERK Kinase (MEK)-Phosphoinositide 3-Kinase Feedback Signaling Determine Susceptibility of Breast Cancer Cells to MEK Inhibition. Cancer Research 69(2): 565-572
Bryan T. Hennessy, Ana-Maria Gonzalez-Angulo, Katherine Stemke-Hale, Michael Z. Gilcrease, Savitri Krishnamurthy, Ju-Seog Lee, Jane Fridlyand, Aysegul Sahin, Roshan Agarwal, Corwin Joy, Wenbin Liu, David Stivers, Keith Baggerly, Mark Carey, Ana Lluch, Carlos Monteagudo, Xiaping He, Victor Weigman, Cheng Fan, Juan Palazzo, Gabriel N. Hortobagyi, Laura K. Nolden, Nicholas J. Wang, Vecente Valero, Joe W. Gray, Charles M. Perou, and Gordon B. Mills ( 2009) Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics. Cancer Research 69(10): 4116-4124
Michael M. Weil, Joel S. Bedford, Helle Bielefeldt-Ohmann, F. Andrew Ray, Paula C. Genik, Eugene J. Ehrhart, Christina M. Fallgren, Fitsum Hailu, Christine L. R. Battaglia, Brad Charles, Matthew A. Callan, and Robert L. Ullrich ( 2009) Incidence of Acute Myeloid Leukemia and Hepatocellular Carcinoma in Mice Irradiated with 1 GeV/nucleon 56Fe Ions. Radiation Research 172: 213-219
Disha Dayal, Sean M. Martin, Kjerstin M. Owens, Nukhet Aykin-Burns, Yueming Zhu, Amutha Boominathan, Debkumar Pain, Charles L. Limoli, Prabhat C. Goswami, Frederick E. Domann, and Douglas R. Spitz ( 2009) Mitochondrial Complex II Dysfunction Can Contribute Significantly to Genomic Instability after Exposure to Ionizing Radiation. Radiation Research 172: 737-745
Yuanlin Peng, Natalie Brown, Rosemary Finnon, Christy L. Warner, Xianan Liu, Paula C. Genik, Matthew A. Callan, F. Andrew Ray, Thomas B. Borak, Christophe Badie, Simon D. Bouffler, Robert L. Ullrich, Joel S. Bedford, and Michael M. Weil ( 2009) Radiation Leukemogenesis in Mice: Loss of PU.1 on Chromosome 2 in CBA and C57BL/6 Mice after Irradiation with 1 GeV/nucleon 56Fe Ions, X Rays or Gamma Rays. Part I. Experimental Observations. Radiation Research 171: 474-483
Seongmi Park, Kimmo J. Hatanpaa, Yang Xie, Bruce E. Mickey, Christopher J. Madden, Jack M. Raisanen, Deepti B. Ramnarain, Guanghua Xiao, Debabrata Saha, David A. Boothman, Dawen Zhao, Robert M. Bachoo, Russell O. Pieper, and Amyn A. Habib ( 2009) The Receptor Interacting Protein 1 Inhibits p53 Induction through NF-KB Activation and Confers a Worse Prognosis in Glioblastoma. Cancer Research 69(7): 2809-2816
Coleman MC, CR Asbury, D Daniels, J Du, N Aykin-Burns, BJ Smith, L Li, DR Spitz, and JJ Cullen ( 2008) 2-Deoxy-D-Glucose Causes Cytotoxicity, Oxidative Stress, and Radiosensitization in Pancreatic Cancer. Free Radical Biology and Medicine 44(3): 322-331
Martinez, A., Hinz, J., Gomez, L., Molina, B., Acuna, H., Frias, S. and Coleman, M.A. ( 2008) Differential expression of TP53 associated genes in Fanconi anemia cells after mitomycin C and hydroxyurea treatment. Mutation Research 656(1-2): 1-7
Pluth, J.M., Yamazaki, V., Cooper, B.A., Rydberg, B.E., Kirchgessner, C.U., and Cooper, P.K. ( 2008) DNA Double-Strand Break and Chromosomal Rejoining Defects with Misrejoining in Nijmegen Breakage Syndrome Cells. DNA Repair 7(1): 108-118
Paunesku, D., Paunesku, T., Wahl, A., Kataoka, Y., Murley, J., Grdina, D.J., and Woloschak, G.E. ( 2008) Incidence of Tissue Toxicities in Gamma Ray and Fission Neutron Exposed Mice Treated with Amifostine. International J. of Radiation Biology 84(8): 623-634
Amundson, S.A., Do, K.T., Vinikoor, L.C., Lee, R.A., Koch-Paiz, C.A., Ahn, J., Reimers, M., Chen, Y., Scudiero, D.A., Weinstein, J.N., Trent, J.M., Bittner, M.L., Meltzer, P.S., and Fornace, A.J., Jr. ( 2008) Integrating Global Gene Expression and Radiation Survival Parameters Across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen. Cancer Research 68(2): 415-424
Kocher, D.C., Apostoaei, A.I., Henshaw, R.W., Hoffman, F.O., Schubauer-Berigan, M.K., Stancescu, D.O., Thomas, B.A., Trabalka, J.R., Gilbert, E.S., and Land, C.E. ( 2008) Interactive Radioepidemiological Program (IREP): A Web-Based Tool for Estimating Probability of Causation/Assigned Share of Radiogenic Cancers. Health Physics 95(1): 119-147
Du, X.X., Yang, F., Manes, N.P., Stenoien, D.L., Monroe, M.E., Adkins, J.N., States, D.J., Purvine, S.O., Camp, D.G., and Smith, R.D. ( 2008) Linear Discriminant Analysis-Based Estimation of the False Discovery Rate for Phosphopeptide Identifications. Journal of Proteome Research 7(6): 2195-2203
Nagasawa, H., Wilson, P.E., Chen, D.J., Thompson, L.H., Bedford, J.S., and Little, J.B. ( 2008) Low Doses of Alpha Particles do not Induce Sister Chromatid Exchanges in Bystander Chinese Hamster Cells Defective in Homologous Recombination. DNA Repair 7(3): 515-522
Elmore, E., Lao, X-Y., Kapadia, R., Giedzinski, E., Limoli, C., and Redpath, J.L. ( 2008) Low Doses of Very Low-Dose-Rate Low-LET Radiation Suppress Radiation-Induced Neoplastic Transformation In Vitro and Induce an Adaptive Response. Radiation Research 169(3): 311-318
Gridley, D.S., Coutrakon, G.B., Rizvi, A., Bayeta, E.J.M., Luo-Owen, X., Makinde, A.Y., Baqai, F., Koss, P., Slater, J.M., and Pecaut, M.J. ( 2008) Low-Dose Photons Modify Liver Response to Simulated Solar Particle Event Protons. Radiation Research 169(3): 280-287
Murley, J.S., Nantajit, D., Baker, K.L., Kataoka, Y., Li, J.J., and Grdina, D.J. ( 2008) Maintenance of Manganese Superoxide Dismutase (SOD2)-Mediated Delayed Radioprotection Induced by Repeated Administration of the Free Thiol Form of Amifostine. Radiation Research 169(5): 495-505
Pichiorri, F., Ishii, H., Okumura, H., Trapasso, F., Wang, Y., and Huebner, K. ( 2008) Molecular Parameters of Genome Instability: Roles of Fragile Genes at Common Fragile Sites. Journal of Cellular Biochemistry 104(5): 1525-1533
Miller, J.H., Jin, S., Morgan, W.F., Yang, A., Wan, Y., Aypar, U., Peters, J.S., and Springer, D.L. ( 2008) Profiling Mitochondrial Proteins in Radiation-Induced Genome-Unstable Cell Lines with Persistent Oxidative Stress by Mass Spectrometry. Radiation Research 169(6): 700-706
Narayan, S., Lehmann, J., Coleman, M.A., Vaughan, A., Yang, C.C., Enepekides, D., Farwell, G., Purdy, J.A., Laredo, G. Nolan, K., Pearson, F. and Vijayakumar, S. ( 2008) Prospective evaluation to establish a dose response for clinical oral mucositis in patients undergoing head and neck conformal radiotherapy. International J. of Radiation: Oncology - Biology - Physics 72: 756-62
Wilson, P.E., Nagasawa, H., Warner, C.L., Fitzek, M.M., Little, J.B., and Bedford, J.S. ( 2008) Radiation Sensitivity of Primary Fibroblasts from Hereditary Retinoblastoma Family Members and Some Apparently Normal Controls: Colony Formation Ability During Continuous Low-Dose-Rate Gamma Irradiation. Radiation Research 169(5): 483-494
Lopez-Ferrer, D., Heibeck, T.H., Petritis, K., Hixson, K.K., Qian, W., Monroe, M.E., Mayampurath, A., Moore, R.J., Belov, M.E., Camp, D.G., and Smith, R.D. ( 2008) Rapid Sample Processing for LC-MS-Based Quantitative Proteomics Using High Intensity Focused Ultrasound. Journal of Proteome Research 7(9): 3860-3867
Venkatachalam, P., de Toledo, S.M., Pandey, B., Tephly, L.A., Carter, A.B., Little, J.B., Spitz, D.R., and Azzam, E.I. ( 2008) Regulation of Normal Cell Cycle Progression by Flavin-Containing Oxidases. Oncogene 27(1): 20-31
Maxwell, C.A., Fleisch, M.C., Costes, S.V., Erickson, A.C., Biossiere, A., Gupta, R., Ravani, S.A., Parvin, B., and Barcellos-Hoff, M.H. ( 2008) Targeted and Nontargeted Effects of Ionizing Radiation that Impact Genomic Instability. Cancer Research 68(20): 8304-8311
Berglund, S.R., Rocke, D.M., Dai, J., Schwietert, C.W., Santana, A., Stern, R.L., Lehmann, J., Hartmann-Siantar, C.L., and Goldberg, Z. ( 2008) Transient Genome-Wide Transcriptional Response to Low-Dose Ionizing Radiation in Vivo in Humans. International J. of Radiation: Oncology - Biology - Physics 70(1): 229-234
Gridley, D.S., Rizvi, A., Luo-Owen, X., Makinde, A.Y., Coutrakon, G.B., Koss, P., Slater, J.M., and Pecaut, M.J. ( 2008) Variable Hematopoietic Responses to Acute Photons, Protons and Simulated Solar Particle Event Protons. In Vivo 22(2): 159-169
Dziegielewski, J., Baulch, J.E., Goetz, W., Coleman, M.C., Spitz, D.R., Murley, J.S., Grdina, D.J., and Morgan, W.F. ( 2008) WR-1065, the Active Metabolite of Amifostine, Mitigates Radiation-Induced Delayed Genomic Instability. Free Radical Biology and Medicine 45(12): 1674-1681
Kato, T.A., Wilson, P.F., Nagasawa, H., Fitzek, M.M., Weil, M.M., Little, J.B., and Bedford, J.S. ( 2007) A Defect in DNA Double Strand Break Processing in Cells from Unaffected Parents of Retinoblastoma Patients and Other Apparently Normal Humans. DNA Repair 6: 818-829.
Day, T.K., Zeng, G., Hooker, A.M., Bhat, M., Scott, B.R., Turner, D.R., and Sykes, P.J. ( 2007) Adaptive Response for Chromosomal Inversions in pKZ1 Mouse Prostate Induced by Low Doses of X Radiation Delivered after a High Dose. Radiation Research 167(6): 682-692
Ahmed, K.M., and Li, J.J. ( 2007) ATM-NF-kappa B connection as a target for tumor radiosensitization. Current Cancer Drug Targets 7(4): 335-342
Stenoien, D.L., Knyushko, T.V., Londono, M.P., Opresko, L.K., Mayer, M.U., Brady, S.T., Squier, T.C., and Bigelow, D.J. ( 2007) Cellular Trafficking of Phospholamban and Formation of Functional Sarcoplasmic Reticulum During Myocyte Differentiation. American Journal of Physiology-Cell Physiology 292(6) : C2084-C2094
Elmore, E., Jain, A., Siddiqui, S., Tohidian, N., Meyskens, F.L., Steele, V.E., and Redpath, J.L. ( 2007) Development and Characteristics of a Human Cell Assay for Screening Agents for Melanoma Prevention. Melanoma Research 17: 42-50
Sedelinkova, O.A., Nakamura, A., Kovalchuk, O., Koturbash, I., Mitchell, S.A., Marino, S.A., Brenner, D.J., and Bonner, W.M. ( 2007) DNA Double-Strand Breaks Form in Bystander Cells After Microbeam Irradiation of Three-Dimensional Human Tissue Models. Cancer Research 67(9): 4295-4302
Perrine, K.A., Lamarche, B.L., Hopkins, D.F., Budge, S.E., Opresko, L. K., Wiley, H.S., and Sowa Resat, M.B. ( 2007) High Speed Method for In Situ Multispectral Image Registration. Microscopy Research and Technique 70: 382-389
Wei, G.W., Ku, S., Ma, G.K., Saito, S., Tang, A.A., Zhang, J., Mao, J.H., Appella, E., Balmain, A., and Huang, E.J. ( 2007) HIPK2 Represses Beta-Catenin-Mediated Transcription, Epidermal Stem Cell Expansion, and Skin Tumorigenesis. PNAS 104(32): 13040-13045
Kumari, I., Andarawewa, K.L., Erickson, A.C., Chou, W.S., Costes, S.V., Gascard, P., Mott, J.D., Bissell, M.J., and Barcellos-Hoff, M.H. ( 2007) Ionizing Radiation Predisposes Nonmalignant Human Mammary Epithelial Cells to Undergo Transforming Growth Factor ß-Induced Epithelial to Mesenchymal Transition. Cancer Research 67(18): 8662-8670
Parvin, B., Yang, Q., Han, J., Chang, H., Rydberg, B., and Barcellos-Hoff, M.H. ( 2007) Iterative Voting for Inference of Structural Saliency and Characterization of Subcellular Events. IEEE Press 16(3): 615-623
Murley, J.S., Kataoaka, Y., Baker, K.L., Diamond, A.M., Morgan, W.F., and Grdina, D.J. ( 2007) Manganese Superoxide Dismutase (SOD2)-Mediated Delayed Radioprotection Induced by the Free Thiol Form of Amifostine and Tumor Necrosis Factor Alpha. Radiation Research 167(4): 465-474
Kleiman, N.J., David, J., Elliston, C.D., Hopkins, K.M., Smilenov, L.B., Brenner, D.J., Worgul, B.V., Hall, E.J., and Lieberman, H.B. ( 2007) Mrad9 and ATM Haploinsufficiency Enhance Spontaneous and X-Ray-Induced Cataractogenesis in Mice. Radiation Research 168(5): 567-573
Prise, K.M., Burdak-Rothkamm, S., Folkard, M., Kashino, G., Shao, C., and Tartier, L. ( 2007) New insights on Radiation-Induced Bystander Signaling and Its Relationship to DNA Repair. International Congress Series 1299: 121-127
Beliveau, A., Bassett, E., Lo, A. T., Garbe, J., Rubio, M. A., Bissell, M. J., Campisi, J., and Yaswen, P. ( 2007) p53-Dependent Integration of Telomere and Growth Factor Deprivation Signals. PNAS 104(11): 4431-4436.
Bladen, C.L., Flowers, M.A., Miyake, K., Podolsky, R.H., Barrett, J.T., Kozlowski, D.J., and Dynan, W.S. ( 2007) Quantification of Ionizing Radiation-Induced Cell Death In Situ in a Vertebrate Embryo. Radiation Research 168(2): 149-157
Ponomarev, A.L., Belli, M., Hahnfeldt, P.J., Hlatky, L., Sachs, R.K., and Cucinotta, F.A. ( 2007) Subtraction of Background Damage in PFGE Experiments on DNA Fragment-Size Distributions. Radiation Environ. Biophys. 46(2) : 155-160
Schmid, T.E., Eskenazi, B., Baumgartner, A., Marchetti, F., Young, S., Weldon, R., Anderson, D., and Wyrobek, A.J. ( 2007) The Effects of Male Age on Sperm DNA Damage in Healthy Non-Smokers. Human Reproduction 22(1) : 180-187
Liu, Y.T., Das, S., Olszewski, R.E., Carpenter, D.A., Culiat, C.T., Sundberg, J.P., Soteropoulos, P., Liu, X., Doktycz, M.J., Michaud, E.J., and Voy, B.H. ( 2007) The Near-Naked Hairless (Hr(N)) Mutation Disrupts Hair Formation But is Not Due to a Mutation in the Hairless Coding Region. Journal of Investigative Dermatology 127(7) : 1605-1614
Brooks, A. L. ( 2007) U.S. Department of Energy low dose radiation research program. BWCHPS Newsletter n.a.: 26-27
Brooks, A.L., Couch, L.A, and Rithidech, K.N. ( 2007) Victor P. Bond (1920-2007): In Memoriam. Radiation Research 168(3): 388-389
Ponomarev, A.L., Belli, M., Hahnfeldt, P., Hlatky, L., Sachs, R.K., and Cucinotta, F.A. ( 2006) A Robust Procedure for Removing Background Damage in Assays of Radiation-Induced DNA Fragment Distributions. Radiation Research 166: 908-916
Kirkby, K.J., Grime, G.W., Webb, P.B., Folkard, M., Prise, K., and Vojnovic, B. ( 2006) A Scanning Focused Vertical Ion Nanobeam: A New UK Facility for Cell Irradiation and Analysis. Radiation Research 166: 654-655.
Yan, B., Wang, H., Peng, Y., Hu, Y., Wang, H., Zhang, X., Chen, Q., Bedford, J.S., Dewhirst, M.W., and Li, C.Y. ( 2006) A Unique Role of the DNA Fragmentation Factor in Maintaining Genomic Stability. PNAS 103(5): 1504-1509
Chuang, E.Y., Chen, X., Tsai, M.-H., Yan, H., Li, C.-Y., Mitchell, J.B., Nagasawa, H., Wilson, P.F., Peng, Y., Fitzek, M.M., Bedford, J.S., and Little, J.B. ( 2006) Abnormal Gene Expression Profiles in Unaffected Parents of Patients with Hereditary-Type Retinoblastoma. Cancer Research 66(7): 3428-3433
Chao, C., Wu, Z., Mazur, S.J., Borges, H., Rossi, M., Lin, T., Wang, J.Y.J., Anderson, C. W., Apella, E., and Xu, Y. ( 2006) Acetylation of Mouse P53 at Lysine 317 Negatively Regulates P53 Apoptotic Activities after DNA Damage. Molecular and Cellular Biology 26: 6859-6869.
Mitchel, R.E.J. ( 2006) Adaptive response in vitro and in vivo and its impact on low-dose radiation risk. In: Advances in Medical Physics: Biological Effects of Low Doses of Ionizing Radiation. Advances in Medical Physics 2006 Chapter 3: 264-270
de Toledo, S.M., Asaad, N., Venkatachalam, P., Li, L., Howell, R.W., Spitz, D.R., and Azzam, E.I. ( 2006) Adaptive Responses to Low-Dose/Low-Dose-Rate [gamma]Rays in Normal Human Fibroblast: The Role of Growth Architecture and Oxidative Metabolism. Radiation Research 166: 849-857
Brooks, A.L., Coleman, MA., Douple, E.B., Hall, E.J., Mitchel, R.E.J., Ullrich, R.L., and Wyrobek, A.J. ( 2006) Biological effects of low doses of ionizing radiation. Advances in Medical Physics 2006 1: 255-286
Shannon, B., Seifert, M., Leskov, K., Willis, J., Boothman, D.A., Tilgen, W., and Reichrath, J. ( 2006) Challenge and Promise: Roles for Clusterin in Pathogenesis, Progression and Therapy of Cancer. Cell Death and Differentiation 13(1): 12-19
Deng, W-P., Chao, M-W., Lai, W-F., Sun, C., Chung, C-Y., Wu, C-C., Lin, I-H., Hwang, J-J., Wu., C-H., Chiu, W-T., Chen, C-Y., and Redpath, J. L. ( 2006) Correction of malignant behavior of tumor cells by traditional Chinese herb medicine through a restoration of p53. Cancer Letters 233: 315-327
Yamaguchi, H., Durell, S.R., Feng, H., Bai, Y., Anderson, C.W., and Appella, E. ( 2006) Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cd, Wip 1. Biochemistry 45: 13192-13202
Coleman, M.A. and Wyrobek, A.J. ( 2006) Differential transcript modulation of genes after low vs. high doses of ionizing radiation. In: Advances in Medical Physics: Biological Effects of Low Doses of Ionizing Radiation. Advances in Medical Physics 2006 Chapter 3: 273-276
Lehmann, J., Stern, R.L., Daly, T.P., Rocke, D.M., Schweitert, C.W., Jones, G.E., Arnold, M.L., Siantar, C.L., and Goldberg, Z. ( 2006) Dosimetry for Quantitative Analysis of the Effects of Low-Dose Ionizing Radiation in Radiation Therapy Patients. Radiation Research 165(2): 240-247
Liddle, R.A. and Jirtle, R.L. ( 2006) Epigenetic silencing of genes in human colon cancer. Gastroenterology 131(3): 960-961
Darakhshan, F., Badie, C., Moody, J., Coster, M., Finnon, R., Finnon, P., Edwards, A.A., Szluinska, M., Skidmore, C.J., Yoshida, K., Ullrich R., Cox, R., and Bouffler, S.D. ( 2006) Evidence for Complex Multigenic Inheritance of Radiation AML Susceptibility in Mice Revealed Using a Surrogate Phenotypic Assay. Carcinogenesis 27(2): 311-318
Paul, S., Gros, L., Laval, J., and Sutherland, B.M. ( 2006) Expression of the E. coli fpg protein in CHO cells lowers endogenous oxypurine clustered damage levels and decreases accumulation of endogenous Hprt mutations. Environmental and Molecular Mutagenesis 47(5): 311-319
Kataoka, Y., Bindokas, V.P., Duggan, R.C., Murley, J.S., and Grdina, D.J. ( 2006) Flow cytometric analysis of phosphorylated histone H2AX following exposure to ionizing radiation in human microvascular endothelial cells. Journal of Radiation Research 47(3-4): 245-257
Kato, T.A., Nagasawa, H., Weil, M.M., Genik, P.C., Little, J.B., and Bedford, J.S. ( 2006) Gamma-H2AX Foci after Low-Dose-Rate Irradiation Reveal Atm Haploinsufficiency in Mice. Radiation Research 166(1): 47-54.
Kadhim, M.A., Hill, M.A., and Moore, S.R. ( 2006) Geonomic instability and the role of radiation quality. Radiation Protection and Dosimetry 122(1-4): 221-227.
Redpath, J.L. ( 2006) Health risks of low photon energy imaging. Radiation Protection and Dosimetry 122(1-4): 221-227.
Ahmed, K.M., Cao, N., and Li, J.J. ( 2006) HER-2 and NF-kappa B as the targets for therapy-resistant breast cancer. Anticancer Research 26(6B) : 4235-4243
Hamada, N., Schettino, G., Kashino, G., Vaid, M., Suzuki, K., Kodama, S., Vojnovic, B., Folkard, M., Watanabe, M., Michael, B.D., and Prise, K.M. ( 2006) Histone H2AX Phosphorylation in Normal Human Cells Irradiated with Focused Ultrasoft X Rays: Evidence for Chromatin Movement during Repair. Radiation Research 166(1) : 31-38
Costes, S.V., Boissiere, A., Ravani, S., Romano, R., Parvin, B., and Barcellos-Hoff, M.H. ( 2006) Imaging features that discriminate between foci induced by high-and low-LET radiation in human fibroblasts. Radiation Research 165(5): 505-515
Sykes, P.J., Day, T.K., Swinburne, S.J., Lane, J.M., Morley, A.A., Hooker, A.M., and Bhat, M. ( 2006) In vivo mutagenic effect of very low dose radiation. Dose Response, An International Journal of the Hormesis Society 4(4): 309-316
Leatherbarrow, E.L., Harper, J.V., Cucinotta, F.A., and O’Neill, P. ( 2006) Induction and quantification of [gamma]-H2AX foci following low- and high-LET irradiation. International J. of Radiation Biology 82(2): 111-118
Wu, H., Hada, M., Meador, J., Hu, X., Rusek, A., and Cucinotta, F.A. ( 2006) Induction of micronuclei in human fibroblasts across the Bragg curve of energetic heavy ions. Radiation Research 166: 583-589
Andrigna, K.K., Coleman, M.C., Aykin-Burns, N., Hitchler, M.J., Walsh, S.A., Domann, F.E., and Spitz, D.R. ( 2006) Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-Deoxy-D-Glucose. Cancer Research 66(3): 1605-1610.
Kirshner, J., Jobling, M.F., Pajeras, M.J., Ravani, S.A., Glick, A.B., Lavin, M.J., Koslov, S., Shiloh, Y., and Barcellos-Hoff, M.H. ( 2006) Inhibition of Transforming Growth Factor-B1 Signaling Attenuates Ataxia Telangiectasia Mutated Activity in Response to Genotoxic Stress. Cancer Research 66(22): 10861-10869
Hall, E.J. ( 2006) Intensity-modulated radiation therapy, protons, and the risk of second cancers. International J. of Radiation: Oncology - Biology - Physics 65(1): 1-7
Brooks, A.L. ( 2006) Introduction to the biological effects of low doses of ionizing radiation. In: Advances in Medical Physics: Biological Effects of Low Doses of Ionizing Radiation. Advances in Medical Physics 2006 Chapter 3: 256.
Koturbash, I., Rugo, R.E., Hendricks, C.A., Loree, J., Thibault, B., Kutanzi, K., Pogribny, I., Yanch, J.C. Engelward, B.P., and Kovalchuk, O. ( 2006) Irradiation Induces DNA Damage and Modulates Epigenetic Effectors in Distant Bystander Tissue in Vivo. Oncogene 25: 4267-4275
Jobling, M.F., Mott, J.D., Finnegan, M.T., Vladimir, J., Erickson, A.C., Walian, P.J., Taylor, S.E., Ledbetter, S., Lawrence, C.M., Rifkin, D.B., and Barcellos-Hoff, M. ( 2006) Isoform-Specific Activation of Latent Transforming Growth Factor ß (LTGF-ß) by Reactive Oxygen Species. Radiation Research 166: 839-848
Slane, B.G., Aykin-Burns, N., Smith, B.J., Kalen, A.L., Goswami, P.C., Domann, F.E., and Spitz, D.R. ( 2006) Mutation of Succinate Dehydrogenase Subunit C Results in Increased O2._, Oxidative Stress, and Genomic Instability. Cancer Research 66(15): 7615-7620
Dunn, J.J., McCorkle, S.R., Everett, L., and Anderson, C.W. ( 2006) Paired-end genomic signature tags: A method for the functional analysis of genomes and epigenomes. Genetic Engineering: Principles and Methods 28: 159-173.
Cornforth, M.N. ( 2006) Perspectives on the formation of radiation-induced exchange aberrations. DNA Repair 5: 1182-1191.
Yang, F., Stenoien, D.L., Strittmatter, E.F., Wang, J., Ding, L., Lipton, M.S., Monroe, M.E., Nicora, C.D., Gristenko, M.A., Tang, K., Fang, R., Adkins, J.N., Camp, D.G. II, Chen, D.J., and Smith, R.D. ( 2006) Phosphoproteome Profiling of Human Skin Fibroblast Cells in Response to Low- and High-Dose Irradiation. Journal of Proteome Research 5: 1252-1260
Zhou, G., Bennett, P.V., Cutter, N.C., and Sutherland, B.M. ( 2006) Proton-HZE-particle sequential dual-beam exposures increase anchorage-independent growth frequencies in primary human fibroblasts. Radiation Research 166: 488-494
Prise, K.M., Folkard, M., and Michael, B.D. ( 2006) Radiation-induced bystander and adaptive responses in cell and tissue options. Dose Response, An International Journal of the Hormesis Society 4(4): 263-276
Gius, D. and Spitz, D.R. ( 2006) Redox signaling in cancer biology. Antioxidants & Redox Signaling 9(7&8): 1249-1252
Hinz, J.M., Tebbs, R.S., Wilson, P.F., Nham, P.B., Saalazar, E.P., Nagasawa, H., Urbin, S.S., Bedford, J.S., and Thompson, L.H. ( 2006) Repression of Mutagenesis of Rad51D-Mediated Homologous Recombination. Nucleic Acids Research 34(5): 1358-1368
Arteaga-Marrero, N., Pallon, J., Auzelyte, V., Elfman, M., Kristiansson, K., Mamlqvist, K., Nilsson, C., and Wegdén, M. ( 2006) Session 1. Development of the Lund Single Ion Hit Facility at the New Sub Micrometer Beam Line. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 655-656.
Braby, L., Brenner, D.J., Cherubini, R., Cremer, T., Durante, M., Geard, C.R., Kobayashi, K., Miller, J.H., Prise, K., and Taucher-Scholz, G. ( 2006) Session 1. Microbeam Probes of Cellular Radiation Response. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 652-653
Garty, G., Ross, G.J., Bigelow, A.W., Schettino, G., Randers-Pherson, G., and Brenner, D.J. ( 2006) Session 1. Status of the Stand-Alone Microbeam at Columbia University. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 656.
Folkard, M., Greubel, C., Hable, V., Dollinger, G., Hauptner, A., Krucken, R., Strickfaden, H., Dietzel, S., Cremer, T., Drexler, G.A., Deutsch, M., and Friedl, A.A. ( 2006) Session 1: Microbeam Source Development, The Munich Microprobe SNAKE, a Single-Ion Cell Irradiation Facility. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 654.
Folkard, M., Atkinson, K.D., Flaccavento, G., Barber, P.R., Locke, R.J., Pierce, G., Gilchrist, S., Michette, A.G., Prise, K.M., and Vojnovic, B. ( 2006) Session 2. Development of the GCI Multitarget X-Ray Microprobe. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 659-660
Botchway, S.W., Harper, J.V., Leatherbarrow, E., Parker, A.W., and O’Neill, P. ( 2006) Session 2. Femtosecond Near Infrared Laser Microbeam Technique for Submicrometer Point Source for High-Resolution Cell DNA Damage, Signaling and Repair Studies. In: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Response. Radiation Research 166: 657-658
Flaccavento, G., Atkinson, K.D., Barber, P.R., Locke, R.J., Pierce, G., Gilchrist, S., Michette, A.G., Prise, K.M., Vojnovic, B., and Folkard, M. ( 2006) Session 2. Performance of the GCI Multitarget X-Ray Microprobe. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 660-661
Barber, P.R., Locke, R.J., Pierce, G.P., Newmann, R.G., Folkard, M., and Vojnovic, B. ( 2006) Session 3. The GCI Multitarget X-Ray Microprobe: Imaging, Control and Software Automation. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 663-664
Moore, S.R., Macdonald, D.A., Folkard, M., Patel, G., Prise, K.M., and Kadhim, M.A. ( 2006) Session 6. Inter-and Intraindividual Differenced in Genomic Instability After Targeted Microbeam Irradiation. Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 678-679
Sedelnikova, O.A., Nakamura, A., Kovalchuk, O., Koturbash, I., Mitchell, S.A., Marino, S.A., Brenner, D.J., and Bonner, W.M. ( 2006) Session 7. Long-Term Biological Bystander Effects of Microbeam Irradiation in 3D Human Tissue Models. Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166: 687
Blakely, E.A., Thompson, A.C., Schwarz, R.I., Chang, P., Bjornstad, K., Rosen, C., Wisnewski, C., Mocherla, D., and Parvin, B. ( 2006) Session 7. Radiation-Induced Bystander Effects with a 12.5 keV X-Ray Microbeam. In: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response. Radiation Research 166(4): 684
Redpath, J.L. ( 2006) Suppression of neoplastic transformation in vitro by low doses of low LET radiation. Dose Response, An International Journal of the Hormesis Society 4(4): 302-308.
Hall, E.J. ( 2006) The bystander effect: Paradigm shifts in interpreting radiation effects. In: Advances in Medical Physics: Biological Effects of Low Doses of Ionizing Radiation. Advances in Medical Physics 2006 Chapter 3: 260.264
Durant, S.T., Paffett, K.S., Shrivastav, M., Timmins, G.S., Morgan, W.F., and Nickoloff, J.A. ( 2006) UV Radiation Induces Delayed Hyperrecombination Associated with Hypermutation in Human Cells. Molecular and Cellular Biology 26(16): 6047-6055
Prise, K.M., Folkard, M., Kuosaite, V., Tartier, L., Zyunzikov, N., and Shao, C. ( 2006) What Role for DNA Damage and Repair in the Bystander Response?. Mutation Research 597(1-2): 1-4
Brooks, A.L. ( 2006) Where have all the limits gone? In: Advances in Medical Physics: Biological Effects of Low Doses of Ionizing Radiation. Advances in Medical Physics 2006 Chapter 3: 276-282.
Brooks, A.L. (Ed.): Wolbarst, A.B., Zamenhof, R., and Hendee, W. ( 2006) Where have all the thresholds gone? In: Chapter 10 Biological effects of low doses of ionizing radiation. Journal of Applied Clinical Medical Physics 7(4): 331
Miller, J.H., Zheng, F., Jin, S., Opresko, L.K., Wiley, H.S., and Resat, H. ( 2005) A Model of Cytokine Shedding Induced by Low Doses of Gamma Radiation. Radiation Research 163(3): 337-342
Weber, T.J., Siegel, R.W., Markillie, L.M., Chrisler, W.B., Lei, X.C., and Colburn, N.H. ( 2005) A paracrine signal mediates the cell transformation response to low dose gamma radiation in JB6 cells. Molecular Carcinogenesis 43: 31-37
Sowa Resat, M.B., Murphy, M.K., Miller, J.H, McDonald, J.C., Strom, D.J., and Kimmel, G.A. ( 2005) A Variable-Energy Electron Microbeam: A Unique Modality for Targeted Low-LET Radiation. Radiation Research 164(5): 695-700
Rithidech, K.N., Tungjai, M., Arbab, E., and Simon, S.R. ( 2005) Activation of NF-kB in Bone Marrow Cells of BALB/cJ Mice Following Exposure In Vivo to Low Doses of (137)Cs Gamma-Rays. Radiation Environ. Biophys. 44: 139-143
Belyakov, O.V., Mitchell, S.A., Parikh, D., Randers-Pehrson, G., Marino, S.A., Amundson, S.A., Geard, C.R., and Brenner, D.J. ( 2005) Biological Effects in Unirradiated Human Tissue Induced by Radiation Damage up to 1mm Away. PNAS 102(40): 14203-14208
Hill, M.A., Ford, J.R., Clapham, P., Marsden, S.J., Stevens, D.L., Townsend, K.M.S., and Goodhead, D.T. ( 2005) Bound PCNA in Nuclei of Primary Rat Tracheal Epithelial Cells after Exposure to Very Low Doses of Plutonium-238 a [alpha] Particles. Radiation Research 163(1): 36-44
Springer, D.L., Ahram, M., Adkins, J.N., Kathmann, L.E., and Miller, J.H. ( 2005) Characterization of Medium Conditioned by Irradiated Cells Using Proteome-Wide, High-Throughput Mass Spectrometry. Radiation Research 164(5): 651-654
Okladnikova, N.D, Scott, B.R., Tokarskaya, Z.B., Zhuntova, G.V., Khokhryakov, V.F., Syrchikov, V.A., and Grigoryeva, E.S. ( 2005) Chromosomal Aberrations in Lymphocytes of Peripheral Blood Among Mayak Facility Workers Who Inhaled Insoluble Forms of 239PU. Radiation Protection and Dosimetry 113(1): 3-13
Brooks, A.L. ( 2005) Chromosome aberrations. In: Twenty-Ninth Hanford Symposium on Health and the Environment, Indoor Radon and Lung Cancer, Reality or Myth? Vol. 1: 606-607
Araki, S., Israel, S., Leskov., K.S., Criswell, T.L., Beman, M., Klokov, D.Y., Sampalth, L., Reinicke, K.E., Cataldo, E., Mayo, L.D., and Boothman, D.A. ( 2005) Clusterin Proteins: Stress-Inducible Polypeptides with Proposed Functions in Multiple Organ Dysfunction. British Institute of Radiology Supplement 27: 106-113
Wang, T., Hu, Y.C., Dong, S.Z., Fan, M., Tamae, D., Ozeki, M., Gao, Q., Gius, D., and Li, J.J. ( 2005) Co-activation of ERK, NF-[kappa]B and GADD45ß[beta] in response to ionizing radiation. Journal of Biological Chemistry 280(13): 12593-12601
Smilenov, L.B., Lieberman, H.B., Mitchell, S.A., Baker, R.A., Hopkins, K.M., and Hall, E.J. ( 2005) Combined Haploinsufficiency for ATM and RAD9 as a Factor in Cell Transformation, Apoptosis, and DNA Lesion Repair Dynamics. Cancer Research 65(3): 933-938
Brooks, A.L. ( 2005) Comments on the article "Possible contribution of 129I in the drinking water and food supply to the nodular formation of thyroid tissue". Health Physics 89(3): 274
Peng, Y., Woods, R.G., Beamish, H., Ye, R., Lees-Miller, S.P., Lavin, M.F., and Bedford, J.S. ( 2005) Deficiency in the Catalytic Subunit of DNA-Dependent Protein Kinase Causes Down-Regulation of ATM. Cancer Research 65(5): 1670-1677
Criswell, T.L., Beman, M., Araki, S., Leskov, K., Cataldo, E., Mayo, L.D., and Boothman, D.A. ( 2005) Delayed Activation of Insulin-Like Growth Factor-1 Receptor/Src/MAPK/Egr-1 Signaling Regulates Clusterin Expression, a Pro-Survival Factor. Journal of Biological Chemistry 280(14): 14212-14221
Zhu, A., Zhou, H., Leloup, C., Marino, S.A., Geard, C.R., Hei, T.K., and Lieberman, H.B. ( 2005) Differential Impact of Mouse Rad9 Deletion on Ionizing Radiation-Induced Bystander Effects. Radiation Research 164: 655-661
Wiese, C., Hinz, J.M., Tebbs, R.S., Nham, P.B., Urin, S.S, Collins, D.W., Thompson, L.H., and Shild, D. ( 2005) Disparate Requirements for the Walker A and B ATPase Motifs of Human RAD51D in Homologous Recombination. Nucleic Acids Research 34(9): 2833-2843
Brenner, D.J. and Mossman, K.L. ( 2005) Do radiation doses below 1 cGy increase cancer risks? Extended Abstracts. Radiation Research 163(6): 692-693
Bennett, P.V., Cuomo, N.L., Paul, S., Tafrov, S.T. and Sutherland, B.M. ( 2005) Endogenous DNA Damage Clusters in Human Skin, 3-D Model, and Cultured Skin Cells. Free Radical Biology and Medicine 39(6): 832-839
Al Rashid, S.T., Dellaire, G., Cuddihy, A., Jalali, F., Vaid, M., Coackley, C., Folkard, M., Xu, Y., Chen, B.P.C., Chen, D.J., Lilge, L., Prise, K.M., Bazett Jones, D.P., and Bristow, R.G. ( 2005) Evidence for the Direct Binding of Phosphorylated P53 to Sites of DNA Breaks In Vivo. Cancer Research 65(23): 10810-10821
Yamamoto, K., Hirano, S., Ishiai, M., Morishima, K., Kitao, H., Namikoshi, K., Kimura, M., Matsushita, N., Arakawa, H., Buerstedde, J-M., Komatsu, K., Thompson, L.H., and Takata, M. ( 2005) Fanconi Anemia Protein FANCD2 Promotes Immunoglobulin Gene Conversion and DNA Repair Through a Mechanism Related to Homologous Recombination. Molecular and Cellular Biology 25(1): 34-43
Brooks, A.L. ( 2005) From cell to organism: The need for multiparametric assessment of exposure and biological effects. British J. of Radiology 27 Suppl.: 139-145
Plan, Y., Hlatky, L., Hahnfeldt, P., Sachs, R.K., Loucas, B., and Cornforth, M.N. ( 2005) Full-Color Painting Reveals an Excess of Radiation-Induced Dicentrics Involving Homologous Chromosomes. International J. of Radiation Biology 81(8): 613-620
Hirano, S., Yamamoto, K., Ishai, M., Yamazoe, M., Seki, M., Matsushita, N., Ohzeki, M., Yamashita, Y.M., Arakawa, H., Buerstedde, J.-M., Enomoto, T., Takeda, S., Thompson, L.H., and Takata, M. ( 2005) Functional Relationships of FANCC to Homologous Recombination, Translesion Synthesis, and BLM. EMBO J 24: 418-427
Ding, L.-H., Shingyoji, M., Chen, F., Hwang, J.-J., Burma, S., Lee, C., Cheng, J.-F., and Chen, D.J. ( 2005) Gene Expression Profiles of Normal Human Fibroblasts after Exposure to Ionizing Radiation: A Comparative Study of Low and High Doses. Radiation Research 164(1): 17-26
Mao, J.H., Li, J., Jiang, T., Li, Q., Wu, D., Perez-Losada, J., DelRosario, R., Peterson, L., Balmain, A., and Cai, W. ( 2005) Genomic Instability in Radiation-Induced Mouse Lymphoma from p53 Heterozygous Mice. Oncogene 24(53): 7924-7934
Ahram, M., Strittmatter, E.F., Monroe, M.E., Adkins, J.N., Hunter, J.C., Miller, J.H., and Springer, D.L. ( 2005) Identification of Shed Proteins from Chinese Hamster Ovary Cells: Application of Statistical Confidence Using Human and Mouse Protein Databases. Proteomics 5: 1815-1826
Coleman, M.A., Yin, E., Peterson, L.E., Nelson, D., Sorensen, K., Tucker, J.D., and Wyrobek, A.J. ( 2005) Low-Dose Irradiation Alters the Transcript Profiles of Human Lymphoblastoid Cells Including Genes Associated with Cytogenetic Radioadaptive Response. Radiation Research 164(4 Pt 1): 369-382
Scott, B.R. ( 2005) Low-dose radiation risk extrapolation fallacy associated with the linear-no-threshold model. Belle Newsletter 13(3-2): 22-27
Sowa Resat, M.B., Kathmann, L.E., Holben, B.A., Thrall, B.D., and Kimmel, G.A. ( 2005) Low-LET microbeam investigation of the track-end dependence of electron-induced damage in normal human diploid fiboblasts. Radiation Research 164(5): 677-679
Zhou, H., Ivanov, V.N., Gillespie, J., Geard, C.R., Amundson, S.A., Brenner, D.J., Yu, Z., Lieberman, H.B., and Hei, T.K. ( 2005) Mechanism of Radiation-Induced Bystander Effect: Role of the Cyclooxygenase-2 Signaling Pathway. PNAS 102(41): 14641-14646
Lynch, D.J., Wilson, W.E., Batdorf, M.T., Sowa Resat, M.B., Kimmel, G.A., and Miller, J.H. ( 2005) Monte Carlo Simulation of the Spatial Distribution of Energy Deposition for An Electron Microbeam. Radiation Research 163(4): 468-472
Elmore, E., Lao, X.Y., Ko, M., Rightnar, S., Nelson, G., and Redpath, J.L. ( 2005) Neoplastic Transformation in Vitro Induced by Low Doses of 232 MeV Protons. International J. of Radiation Biology 81(4): 291-297
Tebbs, R.S., Hinz, J.M., Yamada, N.A., Wilson, J.B., Salazar, E.P., Thomas, C.B., Jones, I.M., Jones, N.J., and Thompson, L.H. ( 2005) New Insights into the Fanconi Anemia Pathway from an Isogenic FancG Hamster CHO Mutant. DNA Repair 4: 11-22
Ridnour, L.A., Sim, J.E., Choi, J., Dickinson, D.A., Forman, H.J., Ahmad, I.M., Coleman, M.C., Hunt, C.R., Goswami, P.C., and Spitz, D.R ( 2005) Nitric Oxide-Induced Resistance to Hydrogen Peroxide Stress is a Glutamate Cysteine Ligase Activity-Dependent Process. Free Radical Biology and Medicine 38: 1361-1371
Grdina, D.J., Murley, J.S., Kataoka, Y., Zhou, D., and Seed, T.M. ( 2005) Radiotherapeutic interactions. Extended Abstracts. Radioprotectors: Current status and new directions. Radiation Research 163: 704-705
Nagasawa, H., Peng, Y., Wilson, P.F., Lio, Y.-C., Chen, D.J., Bedford, J.S., and Little, J.B. ( 2005) Role of Homologous Recombination in the Alpha-Particle-Induced Bystander Effect for Sister Chromatid Exchanges and Chromosomal Aberrations. Radiation Research 164(2): 141-147
Vives, S., Loucas, B., Vazquez, M., Brenner, D.J., Sachs, R.K., Hlatky, I., Cornforth, M.N., and Arsuaga, J. ( 2005) SCHIP: Statistics for Chromosome Interphase Positioning Based on Interchange Data. Bioinformatics 21(14): 3181-3182
Amundson, S.A, Do, K.T., Vinikoor, L., Koch-Paiz, C.A., Bittner, M.L., Trent, J.M., Meltzer, P., and Fornace, A.J., Jr. ( 2005) Stress-Specific Signatures: Expression Profiling of p53 Wild-Type and Null Human Cells. Oncogene 24: 4572-4579
Miller, J.H., Aceves-Gaona,A., Ernst, M.B., Haranczyk,M., Gutowski,M., Vorpagel,E.R., and Dupuis, M. ( 2005) Structure and Energetics of Clustered Damage Sites. Radiation Research 164(4): 582-585.
Yamaguchi, H., Minopoli, G., Demidov, O.N., Chatterjee, D.K., Anderson, C.W., Durell, S.R., and Appella, E. ( 2005) Substrate Specificity of the human Protein Phosphatase 2C, Wip1. Biochemistry 44: 4285-5294.
Zhang, Q., Williams, E.S., Askin, K.F., Peng, Y., Bedford, J.S., Liber, H.L., and Bailey, S.M. ( 2005) Suppression of DNA-PK by RNAi has Different Quantitative Effects on Telomere Dysfunction and Mutagenesis in Human Lymphoblasts Treated with Gamma Rays or HZE Particles. Radiation Research 164: 497-504
Wang, T.L., Tamae, D., LeBon, T., Shively, J.E., Yen, Y., and Li, J.J. ( 2005) The Role of Peroxiredoxin II in Radiation-Resistant MCF-7 Breast Cancer Cells. Cancer Research 65(22) : 10338-10346
Neti, P.V.S.V., de Toledo, S.M., Perumal, V., Azzam, E.I., and Howell, R.W. ( 2004) A Multi-Port Low-Fluence Alpha-Particle Irradiator: Fabrication, Testing and Benchmark Radiobiological Studies. Radiation Research 161: 732-738
Schwartz, J.L. ( 2004) Abandon hope all ye target theory modelers: On the effects of low dose exposures to ionizing radiation and other carcinogens. Mutation Research 568(1): 3-4
Ponnaiya, B., Jenkins-Baker, G., Brenner, D.J., Hall, E.J., Randers-Pehrson, G., and Geard, C.R. ( 2004) Biological responses in known bystander cells relative to known microbeam-irradiated cells. Radiation Research 162(4): 426-432
Mitchell, S.A., Marino, S.A., Brenner, D.J., and Hall, E.J. ( 2004) Bystander effect and adaptive response in C3H 10T(1/2) cells. International J. of Radiation Biology 80(7): 465-472
Lamerdin, J.E., Yamada, N.A., George, J.W., Souza, B., Christian, A.T., Jones, N.J., and Thompson, L.H. ( 2004) Characterization of the Hamster FancG/Xrcc9 Gene and Mutations in CHO UV40 and NM3. Mutagenesis 19(3): 237-244
Arsuaga, J., Greulich-Bodes, K.M., Vazquez, M., Bruckner, M., Hahnfeldt, P., Brenner, D.J., Sachs, R.K., and Hlatky, L. ( 2004) Chromosome Spatial Clustering Inferred from Radiogenic Aberrations. International J. of Radiation Biology 80(7): 507-515
Levy, D., Vazquez, M., Cornforth, M.N., Loucas, B., Sachs, R.K., and Arsuaga, J. ( 2004) Comparing DNA damage-processing pathways by computer analysis of chromosome painting data. Journal of Computational Biology 11(4): 626-641
Rao, R.S., Visuri, S.R., McBride, M.T., Albala, J.S., Matthews, D.L., and Coleman, M.A. ( 2004) Comparison of multiplexed techniques for detection of bacterial and viral proteins. Journal of Proteome Research 3(4): 736-742
Muraoka-Cook, R.S., Kurokawa, H., Koh, Y., Forbes, J.T., Roebuck, L.R., Barcellos-Hoff, M.H., Moody, S.E., Chodosh, L.A., and Arteaga, C.L. ( 2004) Conditional overexpression of active transforming growth factor ß1 in vivo accelerates metastases of transgenic mammary tumors. Cancer Research 64: 9002-9011
Murley, J.S., Kataoka, Y., Cao, D., Li, J.J., Oberley, L.W., and Grdina, D.J. ( 2004) Delayed radioprotection via NF-k[kappa]B-mediated induction of SOD2 (MnSOD) in SA-NH tumor cells following exposure to clinically used thiol-containing drugs. Radiation Research 162(5): 536-546
Tomascik-Cheeseman, L.M., Coleman, M.A., Marcetti, F., Nelson, D.O., Kegelmeyer, L.M., Nath, J., and Wyrobek, A.J. ( 2004) Differential basal expression of genes associated with stress response, damage control, and DNA repair among mouse tissues. Mutation Research 561: 1-14
Bailey, S.M. and Goodwin, E.H. ( 2004) DNA and telomeres: Beginnings and endings. Cytogenetic and Genome Research 104(1-4): 109-115
Wechsler, T., Chen, B.P.C., Harper, R., Morotomi-Yano, K., Huang, B.C.B., Meek, K., Cleaver, J.E., Chen, D.J., and Wabl, M. ( 2004) DNA-PKcs function regulated specifically by protein phosphatase 5. PNAS 101(5): 1247-1252
Brooks, A.L. and Couch, L.A. ( 2004) DOE Program, "Developing a Scientific Basis for Responses to Low Dose Exposures: Impact on Dose-Response Relationships". In: Pacific Basis Nuclear Conference Proceedings, 14th, American Nuclear Society -: -
Bailey, S.M., Cornforth, M.N., Ullrich, R.L., and Goodwin, E.H. ( 2004) Dysfunctional mammalian telomeres join with DNA double-strand breaks. DNA Repair 3(4): 349-357
Goldberg, Z., Schwietert, C.W., Lehnert, B., Stern, R., and Nami, I. ( 2004) Effects of low-dose ionizing radiation on gene expression in human skin biopsies. International J. of Radiation: Oncology - Biology - Physics 58(2): 567-574
Sloter, E., Nath, J., Eskenazi, B., and Wyrobek, A.J. ( 2004) Effects of male age on the frequencies of germinal and heritable chromosomal abnormalities in humans and rodents. Fertility and Sterility 81(4): 925-943
Hinton, T.G., Bedford, J.S., Congdon, J.C., and Whicker, F.W. ( 2004) Effects of radiation on the environment: A need to question old paradigms and enhance collaboration among radiation biologists and radiation ecologists. Radiation Research 162(3): 332-338
Braby, L.A. and Ford, J.R. ( 2004) Energy deposition patterns and the bystander effect. Radiation Research 161(1): 113-114
Brenner, D.J. and Elliston, C.D. ( 2004) Estimated radiation risks potentially associated with full-body CT screening. Radiology 232(3): 735-738
Brooks, A.L. ( 2004) Evidence for "bystander effects" in vivo. Human and Experimental Toxicology 23(2): 67-70
Kashino, G., Prise, K.M., Schettino, G., Folkard, M., Vojnovic, B., Michael, B.D., Suzuki, K., Kodama, S., and Watanabe, M. ( 2004) Evidence for Induction of DNA Double Strand Breaks in the Bystander Response to Targeted Soft X-Rays in CHO Cells. Mutation Research 556(1-2) : 209-215
Loucas, B.D. and Cornforth, M.N. ( 2004) Evidence that unrejoined DNA double-strand breaks are not predominantly responsible for chromosomal radiosensitivity of AT fibroblasts. Radiation Research 162(5): 554-565
Gou, G., Wang, T., Gao, Q., Tamae, D., Wong, P., Chen, T., Chen, W.-C., Shively, J.E., Wong, J.Y.C., and Li, J.J. ( 2004) Expression of ErbB2 enhances radiation-induced NF-?B activation. Oncogene 23: 535-545
Scott, B.R. ( 2004) Health risks from high-level radiation exposures from radiological weapons. Radiation Protection Management 21(6): 9-25
Amundson, S.A., Grace, M.B., McLeland, C.B., Epperly, M.W., Yeager, A., Zhan, Q., Greenberger, J.S. and Fornace, A.J., Jr. ( 2004) Human in Vivo Radiation-Induced Biomarkers: Gene Expression Changes in Radiotherapy Patients. Cancer Research 64: 6368-6371
Chen, W.N.-U., Woodbury, R.L., Kathmann, L.E., Opresko, L.K., Zangar, R.C., Wiley, H.S., and Thrall, B.D. ( 2004) Induced Autocrine Signaling Through the Epidermal Growth Factor Receptor Contributes to the Response of Mammary Epithelial Cells to Tumor Necrosis Factor Alpha. Journal of Biological Chemistry 279(18): 18488-18496
Huang, L., Grim, S., Smith, L.E., Kim, P.M., Nickoloff, J.A., Goloubeva, O.G., and Morgan, W.F. ( 2004) Ionizing Radiation Induces Delayed Hyperrecombination in Mammalian Cells. Molecular and Cellular Biology 24(11): 5060-5068
Klokov, D., Criswell, T.L., Leskov, K.S., Araki, S., Mayo, L., and Boothman, D.A. ( 2004) IR-inducible clusterin gene expression: A protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects. Mutation Research 568(1): 97-110
Miller, J.H. and Zheng, F. ( 2004) Large-scale simulations of cellular signaling processes. Parallel Computing 30(9-10): 1137-1149
Sachs, R.K., Levy, D., Hahnfeldt, P., and Hlatky, L. ( 2004) Quantitative analysis of radiation-induced chromosome aberrations. Cytogenetic and Genome Research 104(1-4): 142-148
Azzam, E.I. ( 2004) Radiation induced adaptive and bystander effects in human and rodent cells exposed to low dose/fluence ionizing radiation. In: The 14th Pacific Basin Nuclear Conference, Honolulu, Hawaii 14th: n.p.
Azzam, E.I. and Little, J.B. ( 2004) Radiation-induced bystander effect: Evidence and significance. Human and Experimental Toxicology 23(2): 61-65
Ozeki, M., Tamea, D., Hou, D.X., Wang, T.L., LeBon, T., Spitz, D.R., and Li, J.J. ( 2004) Response of Cyclin B1 to Ionizing Radiation: Regulation by NF-k[kappa]B and Mitochondrial Antioxidant Enzyme MnSOD. Anticancer Research 24(5A): 2657-2663
Burma, S. and Chen, D.J. ( 2004) Role of DNA-PK in the cellular responses to DNA double-strand breaks. DNA Repair 3(8-9): 909-918
Mitchell, C.R., Azizova, T.V., Hande, M.P., Burak, L.E., Tsakok, J.M., Khokhryakov, V.F., Geard, C.R., and Brenner, D.J. ( 2004) Stable Intrachromosomal Biomarkers of Past Exposure to Densely Ionizing Radiation in Several Chromosomes of Exposed Individuals. Radiation Research 162(3): 257-263
Mitchell, S.A., Randers-Pehrson, G., Brenner, D.J., and Hall, E.J. ( 2004) The bystander response in C3H 10T(1/2) cells: The influence of cell-to-cell contact. Radiation Research 161(4): 397-401
Bailey, S.M., Brenneman, M.A., Halbrook, J., Nickoloff, J.A., Ullrich, R.L., and Goodwin, E.H. ( 2004) The Kinase Activity of DNA-PK is Required to Protect Mammalian Telomeres. DNA Repair 3(3): 225-233
Hooker, A.M., Bhat, M., Day, T.K., Lane, J.M., Swinburne, S.J., Morley, A.A., and Sykes, P.J. ( 2004) The Linear No-Threshold Model Does Not Hold for Low-Dose Ionizing Radiation. Radiation Research 162(4): 447-452
Brooks, A.L. ( 2004) The LNTH is doing more harm than good: Reply to Tschaeche. Journal of Cellular Biochemistry 86(1): 92-93
Yamada, N.A, Hinz, J.M., Kopf, V.L., Segalle, K.D., and Thompson, L.H. ( 2004) XRCC3 ATPase activity is required for normal XRCC3-Rad516 complex dynamics in homologous recombination. Journal of Biological Chemistry 279(22): 23250-23254
Prise, K.M., Folkard, M., and Michael, B.D. ( 2003) Bystander responses induced by low LET radiation. Oncogene 22(45): 7043-7049
Brenner, D.J., Doll, R., Goodhead, D.T., Hall, E.J., Land, C.E., Little, J.B., Lubin, J.H., Preston, D.L., Preston, R.J., Puskin, J.S., Ron, E., Sachs, R.K., Samet, J.M., Setlow, R.B., and Zaider, M. ( 2003) Cancer Risks Attributable to Low Doses of Ionizing Radiation: Assessing What We Really Know. PNAS 100(24): 13761-13766
Brooks, A.L., Lei, X.C., and Rithidech, K.N. ( 2003) Changes in biomarkers from space radiation may reflect dose not risk. Advances in Space Research 31(6): 1505-1512
Klokov, D., Criswell, T.L., Sampath, L., Leskov, K.S., Frinkley, K., Araki, S., Beman, M., Wilson, D.L., and Boothman, D.A. ( 2003) Clusterin: A protein with multiple functions as a potential ionizing radiation exposure marker. Symposium -- 2003 Feb., Nagasaki, Japan, International Consortium for Medical Care of Hibakusha and Radiation Life Science; Radiation and humankind. International Congress Series 1258: 219-232
Flynn, J. and MacGregor, D. ( 2003) Commentary on hormesis and public risk communication: Is there a basis for public discussions?. Human and Experimental Toxicology 22(1): 31-34
DeSimone, J.N., Bengtsson, U., Wang, X.Q., Lao, X.Y., Redpath, J.L., and Stanbridge, E.J. ( 2003) Complexity of the mechanisms of initiation and maintenance of DNA damage-induced G2-arrest and subsequent G1 phase arrest: TP53-dependent and TP53-independent roles. Radiation Research 159(1): 72-85
Donoho, G., Brenneman, M.A., Cui, T.X., Donoviel, D., Vogel, H., Goodwin, E.H., Chen, D.J., and Hasty, P. ( 2003) Deletion of Brca2 Exon 27 Causes Hypersensitivity to DNA Crosslinks, Chromosome Instability, and Reduced Life Span in Mice. Genes, Chromosomes and Cancer 36: 317-331
Brooks, A.L. ( 2003) Developing a scientific basis for radiation risk estimates: Goal of the DOE Low Dose Radiation Research Program. Health Physics 85(1): 85-93
Brooks, A.L. ( 2003) Developing a scientific basis for radiation risk estimates: Major goal of the DOE Low Dose Radiation Research Program. Radiation and Humankind International Congress Series 1258: 287-295
Amundson, S.A., Lee, A., Koch-Paiz, C.A., Bittner, M.L., Meltzer, P., Trent, J. M., and Fornace, A.J., Jr. ( 2003) Differential Responses of Stress Genes to Low Dose-Rate Gamma Irradiation. Molecular Cancer Research 1: 445-452
Coleman, C.N., Stone, H.B., Alexander, G.A., Barcellos-Hoff, M.H., Bedford, J.S., Bristow, R.G., Dynlacht, J.R., Fuks, Z., Gorelic, L.S., Hill, R.P., Joiner, M.C., Liu, F.-F., McBride, W.H., Mckenna, W.G., Powell, S.N., Robbins, M.E.C., Rockwell, S., Schiff, P.B., Shaw, E.G., Siemann, D.W., Travis, E.L., Wallner, P.E., Wong, R.S.L., and Zeman, E.M. ( 2003) Education and training for radiation scientists: Radiation Research Program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12-14, 2003. Radiation Research 160(6): 729-737
Wickliffe, J.K., Bickham, A.M., Rodgers, B.E., Chesser, R.K., Phillips, C.J., Gaschak, S.P., Goryanaya, J.A., Chizhevsky, I., and Baker, R.J. ( 2003) Exposure to Chronic, Low-Dose Rate Gamma-Radiation at Chornobyl Does Not Induce Point Mutations in Big Blue© Mice. Environmental and Molecular Mutagenesis 42(1): 11-18
Yamamoto, K., Ishiai, M., Matsushita, N., Arakawa, H., Lamerdin, J.E., Buerstedde, J., Tanimoto, M., Harada, M., Thompson, L.H., and Takata, M. ( 2003) Fanconi Anemia FANCG Protein in Mitigating Radiation-and Enzyme-Induced DNA Double-Strand Breaks by Homologous Recombination in Vertebrate Cells. Molecular and Cellular Biology 23(15): 5421-5430
McAteer, K. and Kennedy, M.A. ( 2003) Force field dependence of NMR-based, restrained molecular dynamics DNA structure calculations including an analysis of the influence of residual dipolar coupling restraints. Journal of Biomolecular Structure & Dynamics 20(4): 487-506
Barcellos-Hoff, M.H. ( 2003) How radiation-induced phenotypes contribute to neoplastic progression. Health Physics 85(1): 84
Nagasawa, H., Huo, L., and Little, J.B. ( 2003) Increased bystander mutagenic effect in DNA double-strand break repair-deficient mammalian cells. International J. of Radiation Biology 79(1): 35-41
Zhou, H., Randers-Pehrson, G., Geard, C.R., Brenner, D.J., Hall, E.J., and Hei, T.K. ( 2003) Interaction Between Radiation-Induced Adaptive Response and Bystander Mutagenesis in Mammalian Cells. Radiation Research 160(5): 512-516
Park, C.C., Henshall-Powell, R.L., Erickson, A.C., Talhoulk, R., Parvin, B., Bisselll, M.J., Barcellos-Hoff, M.H. ( 2003) Ionizing Radiation Induces Heritable Disruption of Epithelial Cell Interactions. PNAS 100(19): 10
